Mouvement collectif de cellules
vendredi 17 janvier 2014, 11h00 - 12h00
In different biological processes, cells move in a coordinated way.
Several experiments have quantitatively insvestigated this phenomenon. We
will describe a simple model of interacting random walkers that we have
developed to phenomenologically describe these results, based on data
obtained in P Silberzan’s lab (Institut Curie, Paris). The model serves to
suggest some biological mechanisms underlying collective cell motion and
its guidance by leaders cells. It also helps to analyze other observed
phenomena, such as pulsatile behavior and stochastic
reversals of rotational motion in confined cell assemblies.